HtrA-mediated E-cadherin cleavage is limited to DegP and DegQ homologs expressed by gram-negative pathogens

BACKGROUND: The serine proteases HtrA/DegP secreted by the human gastrointestinal pathogens Helicobacter pylori (H. pylori) and Campylobacter jejuni (C. jejuni) cleave the mammalian cell adhesion protein E-cadherin to open intercellular adhesions. A wide range of bacteria also expresses the HtrA/Deg...

Full description

Saved in:
Bibliographic Details
Published in:Cell Commun Signal
Main Authors: Abfalter, Carmen M., Schubert, Maria, Götz, Camilla, Schmidt, Thomas P., Posselt, Gernot, Wessler, Silja
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146865/
https://ncbi.nlm.nih.gov/pubmed/27931258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-016-0153-y
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items