Breast Tumor Kinase (Brk/PTK6) is Induced by HIF, Glucocorticoid Receptor and PELP1 Mediated Stress Signaling in Triple-Negative Breast Cancer

Cancer cells use stress response pathways to sustain their pathogenic behavior. In breast cancer, stress response-associated phenotypes are mediated by the breast tumor kinase, Brk (PTK6), via the hypoxia-inducible factors HIF-1α and HIF-2α. Given that glucocorticoid receptor (GR) is highly expresse...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Cancer Res
Главные авторы: Anderson, Tarah M Regan, Ma, Shihong, Raj, Ganesh V, Cidlowski, John A, Helle, Taylor M, Knutson, Todd P, Krutilina, Raisa I, Seagroves, Tiffany N, Lange, Carol A
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794366/
https://ncbi.nlm.nih.gov/pubmed/26825173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2510
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы