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MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone
Cilia have a unique diffusion barrier (“gate”) within their proximal region, termed transition zone (TZ), that compartmentalises signalling proteins within the organelle. The TZ is known to harbour two functional modules/complexes (Meckel syndrome [MKS] and Nephronophthisis [NPHP]) defined by geneti...
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| Veröffentlicht in: | PLoS Biol |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4794247/ https://ncbi.nlm.nih.gov/pubmed/26982032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002416 |
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