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CEP290 is essential for the initiation of ciliary transition zone assembly

Cilia play critical roles during embryonic development and adult homeostasis. Dysfunction of cilia leads to various human genetic diseases, including many caused by defects in transition zones (TZs), the “gates” of cilia. The evolutionarily conserved TZ component centrosomal protein 290 (CEP290) is...

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Podrobná bibliografie
Vydáno v:PLoS Biol
Hlavní autoři: Wu, Zhimao, Pang, Nan, Zhang, Yingying, Chen, Huicheng, Peng, Ying, Fu, Jingyan, Wei, Qing
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793253/
https://ncbi.nlm.nih.gov/pubmed/33370260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001034
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