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CEP290 is essential for the initiation of ciliary transition zone assembly
Cilia play critical roles during embryonic development and adult homeostasis. Dysfunction of cilia leads to various human genetic diseases, including many caused by defects in transition zones (TZs), the “gates” of cilia. The evolutionarily conserved TZ component centrosomal protein 290 (CEP290) is...
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| Veröffentlicht in: | PLoS Biol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7793253/ https://ncbi.nlm.nih.gov/pubmed/33370260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001034 |
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