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De Novo Synonymous Mutations in Regulatory Elements Contribute to the Genetic Etiology of Autism and Schizophrenia

We analyze de novo synonymous mutations identified in autism spectrum disorders (ASD) and schizophrenia (SCZ) with potential impact on regulatory elements using data from whole exome sequencing (WES) studies. Focusing on five types of genetic regulatory functions, we found that de novo near-splice s...

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Podrobná bibliografie
Vydáno v:Neuron
Hlavní autoři: Takata, Atsushi, Ionita-Laza, Iuliana, Gogos, Joseph A., Xu, Bin, Karayiorgou, Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793939/
https://ncbi.nlm.nih.gov/pubmed/26938441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.02.024
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