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De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia

To evaluate evidence for de novo etiologies in schizophrenia, we sequenced at high coverage the exomes of families recruited from two populations with distinct demographic structure and history. We sequenced a total of 795 exomes from 231 parent-proband trios enriched for sporadic schizophrenia case...

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Detalhes bibliográficos
Main Authors: Xu, Bin, Ionita-Laza, Iuliana, Roos, J. Louw, Boone, Braden, Woodrick, Scarlet, Sun, Yan, Levy, Shawn, Gogos, Joseph A., Karayiorgou, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556813/
https://ncbi.nlm.nih.gov/pubmed/23042115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2446
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