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De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia
To evaluate evidence for de novo etiologies in schizophrenia, we sequenced at high coverage the exomes of families recruited from two populations with distinct demographic structure and history. We sequenced a total of 795 exomes from 231 parent-proband trios enriched for sporadic schizophrenia case...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3556813/ https://ncbi.nlm.nih.gov/pubmed/23042115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2446 |
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