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De Novo Synonymous Mutations in Regulatory Elements Contribute to the Genetic Etiology of Autism and Schizophrenia

We analyze de novo synonymous mutations identified in autism spectrum disorders (ASD) and schizophrenia (SCZ) with potential impact on regulatory elements using data from whole exome sequencing (WES) studies. Focusing on five types of genetic regulatory functions, we found that de novo near-splice s...

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Bibliografiska uppgifter
I publikationen:Neuron
Huvudupphovsmän: Takata, Atsushi, Ionita-Laza, Iuliana, Gogos, Joseph A., Xu, Bin, Karayiorgou, Maria
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793939/
https://ncbi.nlm.nih.gov/pubmed/26938441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.02.024
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