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Exome sequencing supports a de novo mutational paradigm for schizophrenia
Despite high heritability, a large fraction of cases with schizophrenia do not have a family history of the disease (sporadic cases). Here, we examine the possibility that rare de novo protein-altering mutations contribute to the genetic component of schizophrenia by sequencing the exome of 53 spora...
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| Main Authors: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196550/ https://ncbi.nlm.nih.gov/pubmed/21822266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.902 |
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