Inhibition of Chronic Pancreatitis and Murine Pancreatic Intraepithelial Neoplasia by a Dual Inhibitor of c-RAF and Soluble Epoxide Hydrolase in LSL-Kras(G12D)/Pdx-1-Cre Mice

Mutation of Kirsten rat sarcoma viral oncogene homolog (KRAS) and chronic pancreatitis are the most common pathogenic events involved in human pancreatic carcinogenesis. In the process of long-standing chronic inflammation, aberrant metabolites of arachidonic acid play a crucial role in promoting ca...

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Vydáno v:Anticancer Res
Hlavní autoři: LIAO, JIE, HWANG, SUNG HEE, LI, HAONAN, LIU, JUN-YAN, HAMMOCK, BRUCE D., YANG, GUANG-YU
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793710/
https://ncbi.nlm.nih.gov/pubmed/26722025
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