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Atorvastatin inhibits pancreatic carcinogenesis and increases survival in LSL-Kras(G12D)-LSL-Trp53(R172H)-Pdx1-Cre mice

There are several studies supporting the role of HMG-CoA reductase inhibitors such as atorvastatin against carcinogenesis, in which inhibiting the generation of prenyl intermediates involved in protein prenylation plays the crucial role. Mutation of Kras gene is the most common genetic alteration in...

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Detaylı Bibliyografya
Asıl Yazarlar: Liao, Jie, Chung, Yeon Tae, Yang, Allison L, Zhang, Meng, Li, Haonan, Zhang, Wanying, Yan, Liang, Yang, Guang-Yu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411900/
https://ncbi.nlm.nih.gov/pubmed/22549877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.21916
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