Atorvastatin inhibits pancreatic carcinogenesis and increases survival in LSL-Kras(G12D)-LSL-Trp53(R172H)-Pdx1-Cre mice

There are several studies supporting the role of HMG-CoA reductase inhibitors such as atorvastatin against carcinogenesis, in which inhibiting the generation of prenyl intermediates involved in protein prenylation plays the crucial role. Mutation of Kras gene is the most common genetic alteration in...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liao, Jie, Chung, Yeon Tae, Yang, Allison L, Zhang, Meng, Li, Haonan, Zhang, Wanying, Yan, Liang, Yang, Guang-Yu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411900/
https://ncbi.nlm.nih.gov/pubmed/22549877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.21916
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