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Elevation of 2-AG by monoacylglycerol lipase inhibition in the visceral insular cortex interferes with anticipatory nausea in a rat model

Anticipatory nausea (AN) is a conditioned nausea reaction experienced by chemotherapy patients upon returning to the clinic. Currently, there are no specific treatments for this phenomenon, with the classic anti-emetic treatments (e.g., ondansetron) providing no relief. The rat model of AN, contextu...

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Vydáno v:Behav Neurosci
Hlavní autoři: Limebeer, Cheryl L., Rock, Erin M., Puvanenthirarajah, Nirushan, Niphakis, Micah J., Cravatt, Benjamin F., Parker, Linda A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793281/
https://ncbi.nlm.nih.gov/pubmed/26974857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/bne0000132
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