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CDR3β sequence motifs regulate autoreactivity of human invariant NKT cell receptors
Invariant natural killer T (iNKT) cells are a subset of T lymphocytes that recognize lipid ligands presented by monomorphic CD1d. Human iNKT T cell receptor (TCR) is largely composed of invariant Vα24 (Vα24i) TCRα chain and semi-variant Vβ11 TCRβ chain, where complementarity-determining region (CDR)...
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Publicado no: | J Autoimmun |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4792736/ https://ncbi.nlm.nih.gov/pubmed/26748722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2015.12.005 |
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