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Specific roles of each TCR hemichain in generating functional chain-centric TCR
T cell receptor (TCR)α and β chains cooperatively recognize peptide-MHC (pMHC) complexes. It has been shown that a ‘chain-centric’ TCR hemichain can, by itself, dictate MHC-restricted antigen specificity without requiring major contributions from the paired TCR counterchain. Little is known, however...
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| Yayımlandı: | J Immunol |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4369446/ https://ncbi.nlm.nih.gov/pubmed/25710913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401717 |
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