Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain

T cell receptors (TCRs) are used clinically to direct the specificity of T cells to target tumors as a promising modality of immunotherapy. Therefore, cloning TCRs specific for various tumor-associated antigens has been the goal of many studies. To elicit an effective T cell response, the TCR must r...

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Bibliografiska uppgifter
I publikationen:J Vis Exp
Huvudupphovsmän: Guo, Tingxi, Ochi, Toshiki, Nakatsugawa, Munehide, Kagoya, Yuki, Anczurowski, Mark, Wang, Chung-Hsi, Rahman, Muhammed A., Saso, Kayoko, Butler, Marcus O., Hirano, Naoto
Materialtyp: Artigo
Språk:Inglês
Publicerad: MyJove Corporation 2016
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519318/
https://ncbi.nlm.nih.gov/pubmed/27805596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54697
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