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Emerging Functions of Natural IgM and Its Fc Receptor FCMR in Immune Homeostasis

Most natural IgM antibodies are encoded by germline Ig sequences and are produced in large quantities by both mice and humans in the absence of intentional immunization. Natural IgM are reactive with many conserved epitopes, including those shared by microorganisms and autoantigens. As a result, the...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wang, Hongsheng, Coligan, John E., Morse, Herbert C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791374/
https://ncbi.nlm.nih.gov/pubmed/27014278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00099
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