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Glycan-independent binding and internalization of human IgM to FCMR, its cognate cellular receptor
IgM is the first antibody to be produced in immune responses and plays an important role in the neutralization of bacteria and viruses. Human IgM is heavily glycosylated, featuring five N-linked glycan sites on the μ chain and one on the J-chain. Glycosylation of IgG is known to modulate the effecto...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5322398/ https://ncbi.nlm.nih.gov/pubmed/28230186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42989 |
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