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Mouse IgM Fc receptor, FCMR, promotes B cell development and modulates antigen-driven immune responses

FCMR, a Fc receptor specific for pentameric IgM, is expressed at high levels by B cells. Although circulating IgM has profound effects on responses to pathogens, autoimmunity and B cell homeostasis, the biologic consequences of its binding to FCMR are poorly understood. We interrogated FCMR contribu...

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Detalhes bibliográficos
Main Authors: Choi, Seung-Chul, Wang, Hongsheng, Tian, Linjie, Murakami, Yousuke, Shin, Dong-Mi, Borrego, Francisco, Morse, Herbert C., Coligan, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552009/
https://ncbi.nlm.nih.gov/pubmed/23267023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202227
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