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LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer

Tamoxifen, an estrogen receptor (ER) antagonist, is the mainstay treatment of breast cancer and the development of resistance represents a major obstacle for a cure. Although lncRNAs such as HOTAIR have been implicated in breast tumorigenesis, their roles in chemotherapy resistance remain largely un...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Xue, Xingyang, Yang, Yeqing Angela, Zhang, Ali, Fong, Ka-wing, Kim, Jung, Song, Bing, Li, Shangze, Zhao, Jonathan C., Yu, Jindan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791209/
https://ncbi.nlm.nih.gov/pubmed/26364613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.340
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