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LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer

Tamoxifen, an estrogen receptor (ER) antagonist, is the mainstay treatment of breast cancer and the development of resistance represents a major obstacle for a cure. Although lncRNAs such as HOTAIR have been implicated in breast tumorigenesis, their roles in chemotherapy resistance remain largely un...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncogene
Asıl Yazarlar: Xue, Xingyang, Yang, Yeqing Angela, Zhang, Ali, Fong, Ka-wing, Kim, Jung, Song, Bing, Li, Shangze, Zhao, Jonathan C., Yu, Jindan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791209/
https://ncbi.nlm.nih.gov/pubmed/26364613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.340
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