LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer

Tamoxifen, an estrogen receptor (ER) antagonist, is the mainstay treatment of breast cancer and the development of resistance represents a major obstacle for a cure. Although lncRNAs such as HOTAIR have been implicated in breast tumorigenesis, their roles in chemotherapy resistance remain largely un...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Oncogene
Auteurs principaux: Xue, Xingyang, Yang, Yeqing Angela, Zhang, Ali, Fong, Ka-wing, Kim, Jung, Song, Bing, Li, Shangze, Zhao, Jonathan C., Yu, Jindan
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791209/
https://ncbi.nlm.nih.gov/pubmed/26364613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.340
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires