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LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer
Tamoxifen, an estrogen receptor (ER) antagonist, is the mainstay treatment of breast cancer and the development of resistance represents a major obstacle for a cure. Although lncRNAs such as HOTAIR have been implicated in breast tumorigenesis, their roles in chemotherapy resistance remain largely un...
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| Опубликовано в: : | Oncogene |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4791209/ https://ncbi.nlm.nih.gov/pubmed/26364613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.340 |
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