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Efficient and simple generation of multiple unmarked gene deletions in Mycobacterium smegmatis

Research on mycobacterial genetics relies heavily on techniques for directed gene mutation, but genetic studies are often hampered by the difficulty of generating gene deletions in mycobacteria. We developed an efficient and improved deletion system, described here in detail, which can be used to co...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mao, Xu-Jian, Yan, Mei-Yi, Zhu, Hui, Guo, Xiao-Peng, Sun, Yi-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789726/
https://ncbi.nlm.nih.gov/pubmed/26972108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22922
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