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Efficient Generation of Unmarked Deletions in Legionella pneumophila

Unmarked gene deletions facilitate studies of Legionella pneumophila multicomponent processes, such as motility and exonuclease activity. For this purpose, FRT-flanked alleles constructed in Escherichia coli using λ-Red recombinase were transferred to L. pneumophila by natural transformation. Resist...

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Detalhes bibliográficos
Main Authors: Bryan, Andrew, Harada, Kaoru, Swanson, Michele S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067435/
https://ncbi.nlm.nih.gov/pubmed/21296953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02904-10
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