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Influence of cell physiological state on gene delivery to T lymphocytes by chimeric adenovirus Ad5F35

Adoptive transfer of genetically-modified T cells is a promising approach for treatment of both human malignancies and viral infections. Due to its ability to efficiently infect lymphocytes, the chimeric adenovirus Ad5F35 is potentially useful as an immunotherapeutic for the genetic modification of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Wen-feng, Shao, Hong-wei, Wu, Feng-lin, Xie, Xin, Li, Zhu-Ming, Bo, Hua-Ben, Shen, Han, Wang, Teng, Huang, Shu-lin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789598/
https://ncbi.nlm.nih.gov/pubmed/26972139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22688
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