Combination therapy with F5/35 fiber chimeric conditionally replicative adenoviruses expressing IL‐24 enhances the antitumor effect of temozolomide against melanoma

BACKGROUND: Temozolomide (TMZ) is widely used to treat melanoma; however, response rates to TMZ are low because of rapid and frequent resistance. Conditionally, replicative adenoviruses (CRAds) are an effective and promising approach. The receptor for adenovirus is coxsackie‐adenovirus receptor (CAR...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Med
Hauptverfasser: Yang, Ming, Yang, Chunsheng, Tao, Yingkai, Tang, Jianqin, Huang, Qian, Guo, Wenwen, Feng, Shouxin, Jiang, Aijun, Xu, Xifeng, Jiang, Guan, Liu, Yanqun
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Clinical Cancer Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6308089/
https://ncbi.nlm.nih.gov/pubmed/30406970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1843
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