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Combination therapy with F5/35 fiber chimeric conditionally replicative adenoviruses expressing IL‐24 enhances the antitumor effect of temozolomide against melanoma

BACKGROUND: Temozolomide (TMZ) is widely used to treat melanoma; however, response rates to TMZ are low because of rapid and frequent resistance. Conditionally, replicative adenoviruses (CRAds) are an effective and promising approach. The receptor for adenovirus is coxsackie‐adenovirus receptor (CAR...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Med
Hauptverfasser: Yang, Ming, Yang, Chunsheng, Tao, Yingkai, Tang, Jianqin, Huang, Qian, Guo, Wenwen, Feng, Shouxin, Jiang, Aijun, Xu, Xifeng, Jiang, Guan, Liu, Yanqun
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6308089/
https://ncbi.nlm.nih.gov/pubmed/30406970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1843
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