Asymmetric Dimethylarginine in Adult Falciparum Malaria: Relationships With Disease Severity, Antimalarial Treatment, Hemolysis, and Inflammation

Background. Endothelial nitric oxide (NO) bioavailability is impaired in severe falciparum malaria (SM). Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of NO synthase (NOS), contributes to endothelial dysfunction and is associated with mortality in adults with falciparum malaria. Howeve...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Barber, Bridget E., William, Timothy, Grigg, Matthew J., Parameswaran, Uma, Piera, Kim A., Yeo, Tsin W., Anstey, Nicholas M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Major Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789539/
https://ncbi.nlm.nih.gov/pubmed/26985445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofw027
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