Parasite Biomass-Related Inflammation, Endothelial Activation, Microvascular Dysfunction and Disease Severity in Vivax Malaria

Plasmodium vivax can cause severe malaria, however its pathogenesis is poorly understood. In contrast to P. falciparum, circulating vivax parasitemia is low, with minimal apparent sequestration in endothelium-lined microvasculature, and pathogenesis thought unrelated to parasite biomass. However, th...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Barber, Bridget E., William, Timothy, Grigg, Matthew J., Parameswaran, Uma, Piera, Kim A., Price, Ric N., Yeo, Tsin W., Anstey, Nicholas M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287532/
https://ncbi.nlm.nih.gov/pubmed/25569250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004558
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