Nitric Oxide–Dependent Endothelial Dysfunction and Reduced Arginine Bioavailability in Plasmodium vivax Malaria but No Greater Increase in Intravascular Hemolysis in Severe Disease

BACKGROUND: Pathogenesis of severe Plasmodium vivax malaria is poorly understood. Endothelial dysfunction and reduced nitric oxide (NO) bioavailability characterize severe falciparum malaria, but have not been assessed in severe vivax malaria. METHODS: In patients with severe vivax malaria (n = 9),...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Barber, Bridget E., William, Timothy, Grigg, Matthew J., Piera, Kim A., Chen, Youwei, Wang, Hao, Weinberg, J. Brice, Yeo, Tsin W., Anstey, Nicholas M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937019/
https://ncbi.nlm.nih.gov/pubmed/27630198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw427
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