BAG3 regulates contractility and Ca(2+) homeostasis in adult mouse ventricular myocytes

Bcl2-associated athanogene 3 (BAG3) is a 575 amino acid anti-apoptotic protein that is constitutively expressed in the heart. BAG3 mutations, including mutations leading to loss of protein, are associated with familial cardiomyopathy. Furthermore, BAG3 levels have been found to be reduced in end-sta...

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Veröffentlicht in:J Mol Cell Cardiol
Hauptverfasser: Feldman, Arthur M., Gordon, Jennifer, Wang, JuFang, Song, Jianliang, Zhang, Xue-Qian, Myers, Valerie D., Tilley, Douglas G., Gao, Erhe, Hoffman, Nicholas E., Tomar, Dhanendra, Madesh, Muniswamy, Rabinowitz, Joseph, Koch, Walter J., Su, Feifei, Khalili, Kamel, Cheung, Joseph Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789075/
https://ncbi.nlm.nih.gov/pubmed/26796036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.01.015
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