Novel BAG3 Variants in African American Patients with Cardiomyopathy: Reduced β-Adrenergic Responsiveness in Excitation-Contraction.

BACKGROUND. We reported 3 novel non-synonymous single-nucleotide variants of Bcl2-associated athanogene 3 (BAG3) in African Americans with heart failure (HF) which are associated with 2-fold increase in cardiac events (HF hospitalization, heart transplant or death). METHODS. We expressed BAG3 varian...

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Publicado no:J Card Fail
Main Authors: Feldman, Arthur M., Gordon, Jennifer, Wang, JuFang, Song, Jianliang, Zhang, Xue-Qian, Myers, Valerie D., Tomar, Dhanendra, Gerhard, Glenn S., Khalili, Kamel, Cheung, Joseph Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736114/
https://ncbi.nlm.nih.gov/pubmed/32956817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardfail.2020.09.009
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