Structural basis for selective targeting of leishmanial ribosomes: aminoglycoside derivatives as promising therapeutics

Leishmaniasis comprises an array of diseases caused by pathogenic species of Leishmania, resulting in a spectrum of mild to life-threatening pathologies. Currently available therapies for leishmaniasis include a limited selection of drugs. This coupled with the rather fast emergence of parasite resi...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Shalev, Moran, Rozenberg, Haim, Smolkin, Boris, Nasereddin, Abedelmajeed, Kopelyanskiy, Dmitry, Belakhov, Valery, Schrepfer, Thomas, Schacht, Jochen, Jaffe, Charles L., Adir, Noam, Baasov, Timor
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
Materias:
Structural Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787808/
https://ncbi.nlm.nih.gov/pubmed/26264664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv821
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