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When Proteins Start to Make Sense: Fine-tuning Aminoglycosides for PTC Suppression Therapy

Aminoglycosides (AGs) are highly potent antibacterial agents, which are known to exert their deleterious effects on bacterial cells by interfering with the translation process, leading to aberrant protein synthesis that usually results in cell death. Nearly 45 years ago, AGs were shown to induce rea...

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Détails bibliographiques
Auteurs principaux: Shalev, Moran, Baasov, Timor
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136519/
https://ncbi.nlm.nih.gov/pubmed/25147726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4MD00081A
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