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When Proteins Start to Make Sense: Fine-tuning Aminoglycosides for PTC Suppression Therapy

Aminoglycosides (AGs) are highly potent antibacterial agents, which are known to exert their deleterious effects on bacterial cells by interfering with the translation process, leading to aberrant protein synthesis that usually results in cell death. Nearly 45 years ago, AGs were shown to induce rea...

詳細記述

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書誌詳細
主要な著者: Shalev, Moran, Baasov, Timor
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136519/
https://ncbi.nlm.nih.gov/pubmed/25147726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4MD00081A
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