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When Proteins Start to Make Sense: Fine-tuning Aminoglycosides for PTC Suppression Therapy

Aminoglycosides (AGs) are highly potent antibacterial agents, which are known to exert their deleterious effects on bacterial cells by interfering with the translation process, leading to aberrant protein synthesis that usually results in cell death. Nearly 45 years ago, AGs were shown to induce rea...

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Autors principals: Shalev, Moran, Baasov, Timor
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136519/
https://ncbi.nlm.nih.gov/pubmed/25147726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4MD00081A
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