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When Proteins Start to Make Sense: Fine-tuning Aminoglycosides for PTC Suppression Therapy

Aminoglycosides (AGs) are highly potent antibacterial agents, which are known to exert their deleterious effects on bacterial cells by interfering with the translation process, leading to aberrant protein synthesis that usually results in cell death. Nearly 45 years ago, AGs were shown to induce rea...

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Bibliografiske detaljer
Main Authors: Shalev, Moran, Baasov, Timor
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136519/
https://ncbi.nlm.nih.gov/pubmed/25147726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4MD00081A
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