Identification of the molecular attributes required for aminoglycoside activity against Leishmania

Leishmaniasis, a parasitic disease caused by protozoa of the genus Leishmania, affects millions of people worldwide. Aminoglycosides are mostly known as highly potent, broad-spectrum antibiotics that exert their antibacterial activity by selectively targeting the decoding A site of the bacterial rib...

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Bibliographic Details
Main Authors: Shalev, Moran, Kondo, Jiro, Kopelyanskiy, Dmitry, Jaffe, Charles L., Adir, Noam, Baasov, Timor
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746865/
https://ncbi.nlm.nih.gov/pubmed/23898171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307365110
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