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Assembly and analysis of eukaryotic Argonaute–RNA complexes in microRNA-target recognition

Experimental studies have uncovered a variety of microRNA (miRNA)–target duplex structures that include perfect, imperfect and seedless duplexes. However, non-canonical binding modes from imperfect/seedless duplexes are not well predicted by computational approaches, which rely primarily on sequence...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Gan, Hin Hark, Gunsalus, Kristin C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787751/
https://ncbi.nlm.nih.gov/pubmed/26432829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv990
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