Yeast precursor mRNA processing protein PRP19 associates with the spliceosome concomitant with or just after dissociation of U4 small nuclear RNA.

Ítems similars

• The yeast PRP19 protein is not tightly associated with small nuclear RNAs, but appears to associate with the spliceosome after binding of U2 to the pre-mRNA and prior to formation of the functional spliceosome.
  per: Tarn, W Y, et al.
  Publicat: (1993)
• Affinity purification of spliceosomes reveals that the precursor RNA processing protein PRP8, a protein in the U5 small nuclear ribonucleoprotein particle, is a component of yeast spliceosomes.
  per: Whittaker, E, et al.
  Publicat: (1990)
• U4 small nuclear RNA dissociates from a yeast spliceosome and does not participate in the subsequent splicing reaction.
  per: Yean, S L, et al.
  Publicat: (1991)
• Progression through the spliceosome cycle requires Prp38p function for U4/U6 snRNA dissociation.
  per: Xie, J, et al.
  Publicat: (1998)
• PRP38 encodes a yeast protein required for pre-mRNA splicing and maintenance of stable U6 small nuclear RNA levels.
  per: Blanton, S, et al.
  Publicat: (1992)