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Affinity purification of spliceosomes reveals that the precursor RNA processing protein PRP8, a protein in the U5 small nuclear ribonucleoprotein particle, is a component of yeast spliceosomes.

Nuclear pre-mRNA splicing in Saccharomyces cerevisiae, as in higher eukaryotes, occurs in large RNA-protein complexes called spliceosomes. The small nuclear RNA components, U1, U2, U4, U5, and U6, have been extensively studied; however, very little is known about the protein components of yeast spli...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Whittaker, E, Lossky, M, Beggs, J D
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53657/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2138328/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.6.2216
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