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Progression through the spliceosome cycle requires Prp38p function for U4/U6 snRNA dissociation.
The elaborate and energy-intensive spliceosome assembly pathway belies the seemingly simple chemistry of pre-mRNA splicing. Prp38p was previously identified as a protein required in vivo and in vitro for the first pre-mRNA cleavage reaction catalyzed by the spliceosome. Here we show that Prp38p is a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170634/ https://ncbi.nlm.nih.gov/pubmed/9582287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.10.2938 |
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