Progression through the spliceosome cycle requires Prp38p function for U4/U6 snRNA dissociation.

The elaborate and energy-intensive spliceosome assembly pathway belies the seemingly simple chemistry of pre-mRNA splicing. Prp38p was previously identified as a protein required in vivo and in vitro for the first pre-mRNA cleavage reaction catalyzed by the spliceosome. Here we show that Prp38p is a...

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Bibliografiske detaljer
Main Authors: Xie, J, Beickman, K, Otte, E, Rymond, B C
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170634/
https://ncbi.nlm.nih.gov/pubmed/9582287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.10.2938
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