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Yeast precursor mRNA processing protein PRP19 associates with the spliceosome concomitant with or just after dissociation of U4 small nuclear RNA.

During assembly of the spliceosome, the U4 small nuclear RNA (snRNA) interacts with the spliceosome as a preformed U4/U6-U5 triple small nuclear ribonucleoprotein (snRNP) complex. Subsequently, U4 becomes loosely associated with the spliceosome, whereas U5 and U6 remain tightly associated, suggestin...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Tarn, W Y, Lee, K R, Cheng, S C
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47870/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248176/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10821
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