Potent and Targeted Activation of Latent HIV-1 Using the CRISPR/dCas9 Activator Complex

HIV-1 provirus integration results in a persistent latently infected reservoir that is recalcitrant to combined antiretroviral therapy (cART) with lifelong treatment being the only option. The “shock and kill” strategy aims to eradicate latent HIV by reactivating proviral gene expression in the cont...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Ther
मुख्य लेखकों: Saayman, Sheena M, Lazar, Daniel C, Scott, Tristan A, Hart, Jonathan R, Takahashi, Mayumi, Burnett, John C, Planelles, Vicente, Morris, Kevin V, Weinberg, Marc S
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2016
विषय:
Original Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786915/
https://ncbi.nlm.nih.gov/pubmed/26581162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.202
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन