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Genome Engineering Using Adeno-associated Virus: Basic and Clinical Research Applications

In addition to their broad potential for therapeutic gene delivery, adeno-associated virus (AAV) vectors possess the innate ability to stimulate homologous recombination in mammalian cells at high efficiencies. This process—referred to as AAV-mediated gene targeting—has enabled the introduction of a...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Gaj, Thomas, Epstein, Benjamin E, Schaffer, David V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786909/
https://ncbi.nlm.nih.gov/pubmed/26373345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.151
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