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B-cell survival and development controlled by the coordination of NF-κB family members RelB and cRel
Targeted deletion of BAFF causes severe deficiency of splenic B cells. BAFF-R is commonly thought to signal to nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB)–inducing kinase dependent noncanonical NF-κB RelB. However, RelB-deficient mice have normal B-cell numbers. Recent studies...
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| Wydane w: | Blood |
|---|---|
| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society of Hematology
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4786837/ https://ncbi.nlm.nih.gov/pubmed/26773039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-606988 |
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