Acetalins: opioid receptor antagonists determined through the use of synthetic peptide combinatorial libraries.
A synthetic peptide combinatorial library made up of 52,128,400 hexapeptides, each having an acetyl group at the N terminus and an amide group on the C terminus, was screened to find compounds able to displace tritiated [D-Ala2,MePhe4,Gly-ol5]enkephalin from mu opioid receptor binding sites in crude...
Spremljeno u:
| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1993
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47868/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248174/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10811 |
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