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Recursive deconvolution of combinatorial chemical libraries.

A recursive strategy that solves for the active members of a chemical library is presented. A pentapeptide library with an alphabet of Gly, Leu, Phe, and Tyr (1024 members) was constructed on a solid support by the method of split synthesis. One member of this library (NH2-Tyr-Gly-Gly-Phe-Leu) is a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Erb, E, Janda, K D, Brenner, S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45243/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7972077/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.24.11422
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