Direct selection for a catalytic mechanism from combinatorial antibody libraries.

Semisynthetic combinatorial antibody library methodology in the phage-display format was used to select for a cysteine residue in complementarity-determining regions. Libraries were panned with an alpha-phenethyl pyridyl disulfide that undergoes disulfide interchange. Out of 10 randomly picked clone...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Janda, K D, Lo, C H, Li, T, Barbas, C F, Wirsching, P, Lerner, R A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43403/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8146149/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.7.2532
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