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Acetalins: opioid receptor antagonists determined through the use of synthetic peptide combinatorial libraries.

A synthetic peptide combinatorial library made up of 52,128,400 hexapeptides, each having an acetyl group at the N terminus and an amide group on the C terminus, was screened to find compounds able to displace tritiated [D-Ala2,MePhe4,Gly-ol5]enkephalin from mu opioid receptor binding sites in crude...

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Bibliografiska uppgifter
Huvudupphovsmän: Dooley, C T, Chung, N N, Schiller, P W, Houghten, R A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1993
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC47868/
https://ncbi.nlm.nih.gov/pubmed/8248174
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