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The Deubiquitinase Inhibitor PR-619 Sensitizes Normal Human Fibroblasts to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-mediated Cell Death

TNF-related apoptosis-inducing ligand (TRAIL) is a potential cancer therapy that selectively targets cancer cell death while non-malignant cells remain viable. Using a panel of normal human fibroblasts, we characterized molecular differences in human foreskin fibroblasts and WI-38 TRAIL-resistant ce...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Crowder, Roslyn N., Dicker, David T., El-Deiry, Wafik S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786729/
https://ncbi.nlm.nih.gov/pubmed/26757822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.713545
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