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Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II

Membrane-bound cGMP-dependent protein kinase (PKG) II is a key regulator of bone growth, renin secretion, and memory formation. Despite its crucial physiological roles, little is known about its cyclic nucleotide selectivity mechanism due to a lack of structural information. Here, we find that the C...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Campbell, James C., Kim, Jeong Joo, Li, Kevin Y., Huang, Gilbert Y., Reger, Albert S., Matsuda, Shinya, Sankaran, Banumathi, Link, Todd M., Yuasa, Keizo, Ladbury, John E., Casteel, Darren E., Kim, Choel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786703/
https://ncbi.nlm.nih.gov/pubmed/26769964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691303
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